When asked what the first chromosomal abnormality that identified cancer was, one student correctly answered ?

A group of nursing students were studying for their pathophysiology exam by quizzing each other about disorders of WBCs and lymphoid tissue. When asked what the first chromosomal abnormality that identified cancer was, one student correctly answered
Answers:
A. Philadelphia.
B. interleukin cells.
C. BRCA-1.
D. PSA.