Overview of the Mechanisms of Kidney Function

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Ms. Cornwall is admitted with pyelonephritis. She has chills, and her temperature is 101°F. She is complaining of flank pain, frequency, and dysuria. Her urine has white blood cell casts and shows growth of Escherichia coli (E. coli).

Based on the above scenario, answer the following questions:

  • Why does she have bacteria and white blood cell casts in her urine? Include the pathophysiological response of body for your analysis.
  • What are the differences when comparing prerenal acute renal injury, intrarenal acute renal injury, and postrenal acute renal injury? Give examples of each and pathological processes related to each disease process.

Discuss the differences between non-parametric and parametric tests. Provide an example of each and discuss when it is appropriate to use the test. Next, discuss the assumptions that must be met by the investigator to run the test.

Conclude with a brief discussion of your data analysis plan. Discuss the test you will use to address the study hypothesis and which measures of central tendency you will report for demographic variables.

Provide a 250 word answer to the below discussion question in apa format with in-text citations and references:

Conducting research projects while ensuring the protection of human subjects is necessary. What are some methods to protect personal rights of someone in one of the groups that is labeled as vulnerable? Justify your rationale.

Provide constructive, supportive feedback.