Cancer And Diagnosis

Cancer And Diagnosis

J.C. is an 82-year-old white man who was evaluated by a GI specialist due to abdominal discomfort, loss of appetite, weight loss, weakness, and occasional nausea.

Past Medical History (PMH):
Patient is diabetic, controlled with Metformin 500 mg by mouth twice a day, Lantus 15 units SC bedtime. Hypertensive, controlled with Olmesartan 20 mg by mouth once a day. Atrial fibrillation is controlled with Rivaroxaban (15 mg by mouth once a day) and bisoprolol (10 mg by mouth once a day). Cancer And Diagnosis

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Labs:
Hb 12.7 g/dl; Hct 38.8%; WBC 8.2; Glycemia 74 mg/dl; Creatinine 0.8 mg/dl; BUN 9.8 mg/dl; AST 21 U/L; ALT 17 U/L; Bil T 1.90 mg/dl; Ind 0.69 mg/dl; Dir 1.21 mg/dl.

Diagnostic test:
Endoscopic Ultrasound of the Pancreas. Solid mass in the head of the pancreas, 4 cm, infiltrating the Wirsung duct. The solid mass enables it to infiltrate the superior mesenteric vein. A perilesional node is detected, 1.5 cm, metastatic aspect. Fine needle aspiration (FNA) biopsy: ductal adenocarcinoma.

Case study questions:

  1. Please name the potential most common sites for metastasis on J.C. and why.
  2. What are tumor cell markers, and why are tumor cell markers ordered for a patient with pancreatic cancer?
  3. Based on the case study described, proceed to classify the tumor based on the TNM Stage classification. Why is this classification important?
  4. Discussed characteristics of malignant tumors regarding their cells, growth, and ability to spread.
  5. Describe the carcinogenesis phase when a tumor metastasizes.
  6. Choose the tissue level that is affected by the patient discussed above: epithelial, connective, muscular, or neural. Support your answer.

Cancer And Diagnosis