Population Cultural Considerations and Genetic Predispositions NURS-4211

Population Cultural Considerations and Genetic Predispositions NURS-4211

NURS-4211 Role of the Nurse Leader

Week 3 Practicum Group Discussion

Population Cultural Considerations and Genetic Predispositions

This week, you will identify any genetic predisposition your chosen population has to a particular disease and develop primary practice interventions that reflect the cultural considerations of the population. Then, you will develop culturally appropriate, measureable interventions to help your population members maintain an optimal state of health, avoiding the problem that you identified them being at risk for developing.  Population Cultural Considerations and Genetic Predispositions NURS-4211

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Although there are many possible causes of human disease, family history is often one of the strongest risk factors for common disease complexes such as cancer, cardiovascular disease (CVD), diabetes, autoimmune disorders, and psychiatric illnesses. A person inherits a complete set of genes from each parent, as well as a vast array of cultural and socioeconomic experiences from his/her family. Family history is thought to be a good predictor of an individual’s disease risk because family members most closely represent the unique genomic and environmental interactions that an individual experiences (Kardia et al., 2003). Inherited genetic variation within families clearly contributes both directly and indirectly to the pathogenesis of disease. This chapter focuses on what is known or theorized about the direct link between genes and health and what still must be explored in order to understand the environmental interactions and relative roles among genes that contribute to health and illness.

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GENETIC SUSCEPTIBILITY

For more than 100 years, human geneticists have been studying how variations in genes contribute to variations in disease risk. These studies have taken two approaches. The first approach focuses on identifying the individual genes with variations that give rise to simple Mendelian patterns of disease inheritance (e.g., autosomal dominant, autosomal recessive, and X-linked) (see Table 3-1; Mendelian Inheritance in Man). The second approach seeks to understand the genetic susceptibility to disease as the con sequence of the joint effects of many genes. Each of these approaches will be discussed below. Population Cultural Considerations and Genetic Predispositions NURS-4211